Selected publications. For a complete and up-to-date list, see the
PubMed bibliography ↗
* Co-first author · # Corresponding author
2026
2025
Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors.
Kang X, Li X, Zhou J, Zhang Y, Qiu L, Tian C, Deng Z, Liang X, Zhang Z, Du S, Hu S, Wang N, Yue Z, Xu Y, Gao Y, Dai J, Wang Z, Yu C, Chen J, Wu Y, Chen L, Yao Y, Yao S, Yang X, Yan L, Wen Q, Depies OM, Chan K, Liang X, Li G, Zi Z, Liu X, Gan H.
Cell·2025
Proximal proteomics analysis reveals DNA polymerase delta subunit 3 is a new MCM2 binding partner and promotes parental histones inheritance in mammalian cells.
Sun Y, Liang X, Liu F, Zhao W, Zhou J, Li Y, Yao Y, Zhang Z, Li G, Chan K, Zhang D, Wang Z, Gao Y, Yu C, Wu Y, Kang X, Qiu L, Li N, Gan H.
Cell Death & Differentiation·2025
Aberrant heterochromatin silences immune response genes in chronic lymphocytic leukemia.
Depies OM, Guo Q, Gao Y, Sinha S, Ye Z, Han W, Rabe KG, Hoel MS, Darby HC, Yu C, Braggio E, Parikh SA, Slager SL, Kay NE, Wang Z.
Blood Neoplasia·2025
2024
Chronic stress increases metastasis via neutrophil-mediated changes to the microenvironment.
He XY, Gao, Y., Ng D, Michalopoulou E, George S, Adrover JM, Sun L, Albrengues J, Daßler-Plenker J, Han X, Wan L, Wu XS, Shui LS, Huang YH, Liu B, Su C, Spector DL, Vakoc CR, Aelst LV, Egeblad M.#
Cancer Cell·2024
DNA polymerase delta governs parental histone transfer to DNA replication lagging strand.
Tian C, Zhang Q, Jia J, Zhou J, Zhang Z, Karri S, Jiang J, Dickinson Q, Yao Y, Tang X, Huang Y, Guo T, He Z, Liu Z, Gao, Y., Yang X, Wu Y, Chan KM, Zhang D, Han J, Yu C, Gan H.
Proc Natl Acad Sci U S A·2024
Interaction between MED12 and ΔNp63 activates basal identity in pancreatic ductal adenocarcinoma.
Maia-Silva D, Cunniff PJ, Schier AC, Skopelitis D, Trousdell MC, Moresco P, Gao, Y., Kechejian V, He XY, Sahin Y, Wan L, Alpsoy A, Liverpool J, Krainer AR, Egeblad M, Spector DL, Fearon DT, Dos Santos CO, Taatjes DJ, Vakoc CR.
Nature Genetics·2024
2023
ETV6 dependency in Ewing sarcoma by antagonism of EWS-FLI1-mediated enhancer activation.
Gao, Y., He XY, Wu X, Huang Y, Toneyan S, Ipsaro J, Ha T, Koo P, Joshua-Tor L, Bailey K, Egeblad M, Vakoc C.#
Nature Cell Biology·2023
★Featured as the Cover Story for the February issue of
Nature Cell Biology. Highlighted by Prof. Elizabeth R. Lawlor in
Nature Cell Biology.
Impaired histone inheritance promotes tumor progression.
Tian C*, Zhou J*, Li X*, Gao, Y., Wen Q, Kang X, Wang N, Yao Y, Jiang J, Song G, Zhang T, Hu S, Liao J, Yu C, Wang Z, Liu X, Pei X, Chan K, Liu Z, Gan H.#
Nature Communications·2023
2022
Defining the proximity proteome of histone modifications by antibody-mediated Protein A-APEX2 labeling.
Li X, Zhou J, Zhao W, Wen Q, Wang W, Peng H, Gao, Y., Bouchonville KJ, Offer SM, Chan K, Wang Z, Li N, Gan H.
Genomics Proteomics Bioinformatics·2022
2018
2016
2011